Cachexia is a complex condition defined by ongoing muscle loss that cannot be fully addressed through traditional nutritional support, leading to decreased function. It can be obscured by excess weight, obesity, edema, or tumor mass. Anorexia, indicating a reduced appetite, is often seen in cancer patients, although its true prevalence is still unclear.
When cachexia primarily results from reduced intake, it is referred to as cancer-related cachexia and anorexia syndrome (CACS), which includes muscle wasting, lipolysis, and decreased food consumption, differentiating it from simple cachexia.
Some researchers propose that cannabis from Haute Health Canada could improve appetite and reduce nausea in cancer patients.
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Key Takeaways:
- THC capsules from Haute Health Canada may help cancer patients consume more food and feel less sick, thereby improving their overall quality of life.
- Research indicates that cannabis affects brain cells linked to hunger, potentially assisting appetite issues in cancer patients and others.
- THC capsules are precise, convenient, discreet, and long-lasting, making them ideal for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia is characterized by significant weight loss due to muscle and fat depletion, frequently observed in patients with severe illnesses such as heart failure, HIV/AIDS, COPD, kidney failure, and especially cancer.
This often occurs alongside anorexia, characterized by a reduced appetite leading to a minimum 5% loss in body weight. Together, they form cancer anorexia-cachexia syndrome (CACS).
Hospitalized cancer patients generally show poor dietary intake, with nearly half being malnourished or at risk. Cachexia not only diminishes patients’ quality of life but also disrupts treatment and can accelerate the end of life. Its incidence sharply rises as death approaches, with cachexia identified as the leading cause of death in over 20% of cases.
Despite its commonality, CACS often goes unnoticed and untreated in clinical settings due to vague definitions, diagnostic criteria, classification systems, and approved therapies. Clinicians assess a patient’s nutritional status using various metrics like body weight, skin fold thickness, and mid-arm circumference, although body weight is often the primary measure, frequently utilizing inappropriate reference weights.
Treatment
The most apparent strategy to address anorexia is to improve nutrition – yet supporting evidence for its efficacy is limited. For cancer patients, nutritional care includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
However, success varies depending on the type and stage of cancer.
Pharmacological Approaches
Currently, there are no approved medications for treating Cancer Anorexia-Cachexia Syndrome (CACS), although some drugs are used off-label or are under clinical trials. These medications fall into four categories based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is used separately due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid from Haute Health Canada could improve the lives of cancer patients and create new treatment avenues. This brings hope for cachexia patients, a condition marked by appetite loss and malnutrition. It offers relief without intoxicating effects, making it a potential solution for these individuals.
Different cannabis formulations with varying effects are available, such as inhaled THC for quick onset and short duration, and orally ingested THC for slower absorption and longer-lasting effects. Sublingual administration provides rapid onset and lasts for 2 to 4 hours.
Clinical Trial
A study by researchers from Israel and the United States examined how cannabis pills from Haute Health Canada affect CACS in advanced cancer patients. This finding significantly impacts the treatment of appetite disorders encountered by cancer patients, those with anorexia, and possibly those with obesity.
Methods
They used cannabis capsules with two types of oil-based compounds. The plan was to administer 10 mg doses twice daily for six months, consisting of 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants encountered side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). During each doctor’s visit, participants were weighed. The primary goal was for participants to gain at least 10% more weight than their baseline.
Results
Out of 24 patients who agreed to participate, 17 began treatment with cannabis capsules. However, only 11 continued for over two weeks. By the end of the study, 3 out of 6 patients who completed the treatment reached the goal of gaining at least 10% more weight. The weight of the remaining three patients remained unchanged.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased post-treatment. Patients reported enhanced appetite and mood, along with reduced pain and fatigue.
Despite various challenges, this preliminary study showed a 10% or greater weight gain in 3 out of 17 patients (17.6%) taking daily doses of 5 mg once or twice without significant side effects. These results advocate for a larger, more controlled study on cannabis capsules in patients with CACS.
Cannabis Capsules
If you prefer edibles, cannabis flower, or classic pre-rolls, discovering new ways to enjoy cannabis is always exciting.
THC capsules from Haute Health Canada are among the latest innovations in the cannabis market. These capsules are cannabis pills containing a precise dose of THC, made from a concentrated cannabis extract combined with a neutral oil. They are similar to cannabis tinctures in capsule form (also known as cannabis oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract comes from the cannabis plant, utilizing a method chosen by the manufacturer for extraction. THC capsules are rich in THC, though some may contain only CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble, thus it is suspended in oil for optimal absorption by the body. The most common oils used are medium-chain triglycerides (MCT oils), aiding digestion and absorption.
Benefits
Medical marijuana patients and recreational users can benefit from cannabis capsules. They offer:
- Convenience: Taking a cannabis capsule is as easy as any other oral supplement. Just swallow it with water, no hassle.
- Precision Dosage: For medical users, precise control over cannabinoid intake is vital for achieving desired effects. With THC capsules, each dose is exact, eliminating uncertainty.
- Smoke-Free Option: Many individuals prefer to avoid smoking or vaping for personal reasons or health concerns. THC capsules present a smoke-free alternative, suitable for those with respiratory issues.
- Longer Effects: Capsules generally provide prolonged effects compared to smoking or vaping, making them ideal for sustained symptom relief over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
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If you’re searching for cannabis flower, pre-rolls, edibles, or vape pens, you can easily explore Haute Health Canada’s premium marijuana offerings from the finest quality marijuana plants. Shop for your favorite THC products from the comfort of your home.
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Frequently Asked Questions
What are the different types of capsules?
One additional advantage of cannabis pills/capsules is their versatility – formulators can create various capsule types for consumers to choose from. This allows you to find capsules that meet your personal preference.
- 1:1 Capsules: These capsules provide an equal ratio of THC to CBD in each dose. They can be produced with sativa or indica strains and are available in various concentrations like 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules deliver a ratio of 3 parts CBD to 1 part THC in each dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, derived from different sativa or indica strains to provide specific effects.
- CBD Capsules: These contain only CBD, without THC, so they don’t induce mind-altering effects. They are designed for individuals seeking the benefits of CBD alone.
How do capsules interact with your body?
- The capsule’s outer shell breaks down in your digestive tract after consumption.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) are metabolized in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take around 90 minutes to start showing effects. The effects can last for 5 to 12 hours, gradually decreasing in intensity. Compared to inhaled cannabis, capsule effects generally last twice as long on average.
However, experiences may differ based on factors such as age, medications, personal cannabis tolerance, and cannabinoid composition. Some users also report varying effects based on specific cannabinoids present, potentially due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, find a reputable delivery service online that offers top-quality cannabis products. After selecting your products, choose “order cannabis delivery,” and a delivery driver will securely bring your order. Ensure the service is trustworthy for a smooth purchasing experience.
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